Ketamine helps you rewire your neural connections rapidly and safely by beginning a process leading to increased production of brain-derived neurotrophic factor (BDNF)—a protein that increases neuroplasticity and synaptogenesis. It creates a perfect foundation for your work with a therapist. We admi nister controlled sub-anesthetic doses of ketamine through an IV in our restorative, spa-like clinics under constant medical supervision. Infusions range from one to several hours, depending on the diagnosis, and patients describe their experiences as relaxing and peaceful.